Could you even imagine at the first place? Meredith and Derek… Like Meredith said, “a one night stand becomes the love of your life”.

Izzie and Alex, Izzie left, but at the beginning, the were like… enemies. How would have thought they will marry someday?

Cristina and Owen, a crazy guy who showed up from no where and became the love of her life! and the way that they met each other, he was in an ambulance! 

Callie and Arizona, all those ups and downs, the accident thing and all those stuff…  and finally the got married! but when Arizona came as a doctor that Bailey hated, who could’ve imagined that she will marry Callie soon?

and the tragedy of Mark Sloan and little Grey… it took a long time for them to get together (almost like all of the couples above, but unlike Callie & Arizona) , and no one ever thought that the great Mark Sloan would fall for the sweet & cute little sister of Meredith. and they really belonged together, Mark even died in order to be with her.


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